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Department of Urology

John S. Witte, PhD

Recent Publications

Publications – 2008

Cheng, I., S.J. Plummer, E. Jorgenson, X. Liu, B.A. Rybicki, G. Casey, and J.S. Witte, 8q24 and prostate cancer: association with advanced disease and meta-analysis. Eur J Hum Genet, 2008.
 

Publications – 2007

Chen, G.K. and J.S. Witte, Enriching the analysis of genomewide association studies with hierarchical modeling. Am J Hum Genet, 2007. 81(2): p. 397-404.
Chen, G.K., T. Zheng, J.S. Witte, E.L. Goode, L. Gao, P. Hu, Y.J. Suh, B. Suktitipat, S. Szymczak, J.H. Woo, and W. Zhang, Genome-wide association analyses of expression phenotypes. Genet Epidemiol, 2007. 31 Suppl 1: p. S7-S11.
Cheng, I., L.M. Krumroy, S.J. Plummer, G. Casey, and J.S. Witte, MIC1 and IL1RN Genetic Variation and Advanced Prostate Cancer Risk. Cancer Epidemiol Biomarkers Prev, 2007. 16(6): p. 1309-11.
Cheng, I., X. Liu, S.J. Plummer, L.M. Krumroy, G. Casey, and J.S. Witte, COX2 genetic variation, NSAIDs, and advanced prostate cancer risk. Br J Cancer, 2007. 97(4): p. 557-61.
Cheng, I., S.J. Plummer, G. Casey, and J.S. Witte, Toll-like receptor 4 genetic variation and advanced prostate cancer risk. Cancer Epidemiol Biomarkers Prev, 2007. 16(2): p. 352-5.
Jorgenson, E., S.R. Deitcher, M. Cicek, X. Liu, S. Plummer, G. Casey, and J.S. Witte, Plasminogen activator inhibitor type-1 (PAI-1) polymorphism 4G/5G is associated with prostate cancer among men with a positive family history. Prostate, 2007. 67(2): p. 172-7.
Jorgenson, E. and J.S. Witte, Genome-wide association studies of cancer. Future Oncol, 2007. 3(4): p. 419-27.
Liu, X., M.S. Cicek, S.J. Plummer, E. Jorgenson, G. Casey, and J.S. Witte, Association of testis derived transcript gene variants and prostate cancer risk. J Urol, 2007. 177(3): p. 894-8.
Liu, X., F.R. Schumacher, S.J. Plummer, E. Jorgenson, G. Casey, and J.S. Witte, Trans Fatty Acid Intake and Increased Risk of Advanced Prostate Cancer: Modification by RNASEL R462Q Variant. Carcinogenesis, 2007.
Thomas, D.C., J.S. Witte, and S. Greenland, Dissecting effects of complex mixtures: who's afraid of informative priors? Epidemiology, 2007. 18(2): p. 186-90.
Witte, J.S., Multiple prostate cancer risk variants on 8q24. Nat Genet, 2007. 39(5): p. 579-80.
Witte, J.S., A.H. Schnell, H.J. Cordell, R.S. Spielman, C.I. Amos, M.B. Miller, L. Almasy, and J.W. MacCluer, Introduction to Genetic Analysis Workshop 15 summaries. Genet Epidemiol, 2007. 31 Suppl 1: p. S1-6.
 

Publications – 2006

Casey, G., P.J. Neville, X. Liu, S.J. Plummer, M.S. Cicek, L.M. Krumroy, A.P. Curran, M.R. McGreevy, W.J. Catalona, E.A. Klein, and J.S. Witte, Podocalyxin variants and risk of prostate cancer and tumor aggressiveness. Hum Mol Genet, 2006. 15(5): p. 735-41.
Cicek, M.S., X. Liu, F.R. Schumacher, G. Casey, and J.S. Witte, Vitamin D receptor genotypes/haplotypes and prostate cancer risk. Cancer Epidemiol Biomarkers Prev, 2006. 15(12): p. 2549-52.
Jorgenson, E. and J.S. Witte, Coverage and power in genomewide association studies. Am J Hum Genet, 2006. 78(5): p. 884-8.
Jorgenson, E. and J.S. Witte, A gene-centric approach to genome-wide association studies. Nat Rev Genet, 2006. 7(11): p. 885-91.
Liu, X., S.J. Plummer, N.L. Nock, G. Casey, and J.S. Witte, Nonsteroidal antiinflammatory drugs and decreased risk of advanced prostate cancer: modification by lymphotoxin alpha. Am J Epidemiol, 2006. 164(10): p. 984-9.
Nock, N.L., M.S. Cicek, L. Li, X. Liu, B.A. Rybicki, A. Moreira, S.J. Plummer, G. Casey, and J.S. Witte, Polymorphisms in estrogen bioactivation, detoxification and oxidative DNA base excision repair genes and prostate cancer risk. Carcinogenesis, 2006.
Nock, N.L., X. Liu, M.S. Cicek, L. Li, F. Macarie, B.A. Rybicki, S.J. Plummer, G.T. Maclennan, G. Casey, and J.S. Witte, Polymorphisms in polycyclic aromatic hydrocarbon metabolism and conjugation genes, interactions with smoking and prostate cancer risk. Cancer Epidemiol Biomarkers Prev, 2006. 15(4): p. 756-61.
Sapru, A., J.L. Wiemels, J.S. Witte, L.B. Ware, and M.A. Matthay, Acute lung injury and the coagulation pathway: Potential role of gene polymorphisms in the protein C and fibrinolytic pathways. Intensive Care Med, 2006. 32(9): p. 1293-303.
Tung, J.Y., M.P. Rosen, L.M. Nelson, P.J. Turek, J.S. Witte, D.W. Cramer, M.I. Cedars, and R.A. Pera, Variants in Deleted in AZoospermia-Like (DAZL) are correlated with reproductive parameters in men and women. Hum Genet, 2006. 118(6): p. 730-740.
Tung, J.Y., M.P. Rosen, L.M. Nelson, P.J. Turek, J.S. Witte, D.W. Cramer, M.I. Cedars, and R.A. Reijo-Pera, Novel missense mutations of the Deleted-in-AZoospermia-Like (DAZL) gene in infertile women and men. Reprod Biol Endocrinol, 2006. 4: p. 40.