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Department of Urology

Mack Roach III, MD

Recent Publications

Publications – 2008

Chan, L.W., P. Xia, A.R. Gottschalk, M. Akazawa, M. Scala, B. Pickett, I.-C. Hsu, J. Speight, and M. Roach, Proposed Rectal Dose for Patients Undergoing Definitive Whole Pelvic Radiotherapy for Clinically Localized Prostate Cancer. International Journal of Radiation Oncology, Biology, Physics, 2008.
D'Ambrosio, D.J., A. Pollack, E.E. Harris, R.A. Price, Jr., L.J. Verhey, M. Roach, 3rd, D.J. Demanes, M.L. Steinberg, L. Potters, P.E. Wallner, and A. Konski, Assessment of external beam radiation technology for dose escalation and normal tissue protection in the treatment of prostate cancer. Int J Radiat Oncol Biol Phys, 2008. 70(3): p. 671-7.
Lometti, M.W., D. Thurston, M. Aubin, A. Bock, L. Verhey, J.M. Lockhart, R. Bland, J. Pouliot, and M. Roach, 3rd, Are lateral electronic portal images adequate for accurate on-line daily targeting of the prostate? Results of a prospective study. Med Dosim, 2008. 33(1): p. 22-9.
McKenna, D.A., F.V. Coakley, A.C. Westphalen, S. Zhao, Y. Lu, E.M. Webb, B. Pickett, M. Roach, 3rd, and J. Kurhanewicz, Prostate Cancer: Role of Pretreatment MR in Predicting Outcome after External-Beam Radiation Therapy--Initial Experience. Radiology, 2008.
Roach, M., 3rd, K. Bae, J. Speight, H.B. Wolkov, P. Rubin, R.J. Lee, C. Lawton, R. Valicenti, D. Grignon, and M.V. Pilepich, Short-term neoadjuvant androgen deprivation therapy and external-beam radiotherapy for locally advanced prostate cancer: long-term results of RTOG 8610. J Clin Oncol, 2008. 26(4): p. 585-91.
Roach, M., H. Chung, and J.L. Speight, Intermediate-risk and Locally Advanced Prostate Cancer, in Principles and Practice of Radiation Oncology, E. Halperin, C. Perez, and L. Brady, Editors. 2008, Lippincott, Williams and Wilkins.
Shinohara, K. and M. Roach, 3rd, Technique for Implantation of Fiducial Markers in the Prostate. Urology, 2008. 71(2): p. 196-200.
Taussky, D., K. Bae, J.P. Bahary, M. Roach, 3rd, C.A. Lawton, W.U. Shipley, and H.M. Sandler, Does Timing of Androgen Deprivation Influence Radiation-Induced Toxicity? A Secondary Analysis of Radiation Therapy Oncology Group Protocol 9413. Urology, 2008.
 

Publications – 2007

Bermudez, R.S., A. Izaguirre, and M. Roach, 3rd, State-of-the-art radiotherapy in the management of clinically localized prostate carcinoma. Future Oncol, 2007. 3(1): p. 103-11.
Frank, S.J., P.D. Grimm, J.E. Sylvester, G.S. Merrick, B.J. Davis, A. Zietman, B.J. Moran, D.C. Beyer, M. Roach, 3rd, D.H. Clarke, R.G. Stock, W. Robert Lee, J.M. Michalski, K.E. Wallner, M. Hurwitz, L. Potters, D.A. Kuban, B.R. Prestidge, R. Vera, S. Hathaway, and J.C. Blasko, Interstitial implant alone or in combination with external beam radiation therapy for intermediate-risk prostate cancer: a survey of practice patterns in the United States. Brachytherapy, 2007. 6(1): p. 2-8.
Lawton, C.A., M. Desilvio, M. Roach, 3rd, V. Uhl, R. Kirsch, M. Seider, M. Rotman, C. Jones, S. Asbell, R. Valicenti, S. Hahn, and C.R. Thomas, Jr., An Update of the Phase III Trial Comparing Whole Pelvic to Prostate Only Radiotherapy and Neoadjuvant to Adjuvant Total Androgen Suppression: Updated Analysis of RTOG 94-13, with Emphasis on Unexpected Hormone/Radiation Interactions. Int J Radiat Oncol Biol Phys, 2007.
Lawton, C.A., M. DeSilvio, M. Roach, 3rd, V. Uhl, R. Kirsch, M. Seider, M. Rotman, C. Jones, S. Asbell, R. Valicenti, S. Hahn, and C.R. Thomas, Jr., An update of the phase III trial comparing whole pelvic to prostate only radiotherapy and neoadjuvant to adjuvant total androgen suppression: updated analysis of RTOG 94-13, with emphasis on unexpected hormone/radiation interactions. Int J Radiat Oncol Biol Phys, 2007. 69(3): p. 646-55.
Lee, B., K. Shinohara, V. Weinberg, A.R. Gottschalk, J. Pouliot, M. Roach, 3rd, and I.C. Hsu, Feasibility of high-dose-rate brachytherapy salvage for local prostate cancer recurrence after radiotherapy: the University of California-San Francisco experience. Int J Radiat Oncol Biol Phys, 2007. 67(4): p. 1106-12.
Litzenberg, D.W., T.R. Willoughby, J.M. Balter, H.M. Sandler, J. Wei, P.A. Kupelian, A.A. Cunningham, A. Bock, M. Aubin, M. Roach, 3rd, K. Shinohara, and J. Pouliot, Positional Stability of Electromagnetic Transponders Used for Prostate Localization and Continuous, Real-Time Tracking. Int J Radiat Oncol Biol Phys, 2007.
Ludlum, E., G. Mu, V. Weinberg, M. Roach, 3rd, L.J. Verhey, and P. Xia, An algorithm for shifting MLC shapes to adjust for daily prostate movement during concurrent treatment with pelvic lymph nodes. Med Phys, 2007. 34(12): p. 4750-6.
Meyer, J.L., S. Leibel, M. Roach, and S. Vijayakumar, New technologies for the radiotherapy of prostate cancer. A discussion of clinical treatment programs. Front Radiat Ther Oncol, 2007. 40: p. 315-37.
Mohler, J., R.J. Babaian, R.R. Bahnson, B. Boston, A. D'Amico, J.A. Eastham, R.J. Hauke, R.P. Huben, P. Kantoff, M. Kawachi, M. Kuettel, P.H. Lange, C. Logothetis, G. MacVicar, A. Pollack, J.M. Pow-Sang, M. Roach, 3rd, H. Sandler, D. Shrieve, S. Srinivas, P. Twardowski, D.A. Urban, and P.C. Walsh, Prostate cancer. Clinical practice guidelines in oncology. J Natl Compr Canc Netw, 2007. 5(7): p. 650-83.
Roach, M., 3rd, Dose escalated external beam radiotherapy versus neoadjuvant androgen deprivation therapy and conventional dose external beam radiotherapy for clinically localized prostate cancer: do we need both? Strahlenther Onkol, 2007. 183 Spec No 2: p. 26-8.
Roach, M., 3rd, Editorial Comment on: High Provider Volume is Associated with Lower Rate of Secondary Therapies after Definitive Radiotherapy for Localized Prostate Cancer. Eur Urol, 2007.
Roach, M., 3rd, Regarding the influence of adjuvant suppression therapy for prostate cancer on the frequency and timing of fatal myocardial infarction: how real is the risk? J Clin Oncol, 2007. 25(33): p. 5325-6; author reply 5326.
Roach, M., 3rd, M. De Silvio, T. Rebbick, D. Grignon, M. Rotman, H. Wolkov, B. Fisher, G. Hanks, W.U. Shipley, A. Pollack, H. Sandler, and D. Watkins-Bruner, Racial Differences in CYP3A4 Genotype and Survival Among Men Treated on Radiation Therapy Oncology Group (RTOG) 9202: A Phase III Randomized Trial. Int J Radiat Oncol Biol Phys, 2007.
Roach, M., 3rd and A. Izaguirre, Goserelin acetate in combination with radiotherapy for prostate cancer. Expert Opin Pharmacother, 2007. 8(2): p. 257-64.
Roach, M., 3rd, V. Weinberg, H. Sandler, and I. Thompson, Staging for prostate cancer: time to incorporate pretreatment prostate-specific antigen and Gleason score? Cancer, 2007. 109(2): p. 213-20.
Sahgal, A. and M. Roach, 3rd, Permanent prostate seed brachytherapy: a current perspective on the evolution of the technique and its application. Nat Clin Pract Urol, 2007. 4(12): p. 658-70.
Schiffner, D.C., A.R. Gottschalk, M. Lometti, M. Aubin, J. Pouliot, J. Speight, I.C. Hsu, K. Shinohara, and M. Roach, 3rd, Daily electronic portal imaging of implanted gold seed fiducials in patients undergoing radiotherapy after radical prostatectomy. Int J Radiat Oncol Biol Phys, 2007. 67(2): p. 610-9.
Speight, J.L. and M. Roach, 3rd, Advances in the treatment of localized prostate cancer: the role of anatomic and functional imaging in men managed with radiotherapy. J Clin Oncol, 2007. 25(8): p. 987-95.
Speight, J.L. and M. Roach, Radiotherapy of Urologic Tumors, in Smith’s General Urology, J. McAnnich and E. Tanagho, Editors. 2007, Lange Medical Books/McGraw-Hill.
Stone, N.N., L. Potters, B.J. Davis, J.P. Ciezki, M.J. Zelefsky, M. Roach, P.A. Fearn, M.W. Kattan, and R.G. Stock, Customized dose prescription for permanent prostate brachytherapy: insights from a multicenter analysis of dosimetry outcomes. Int J Radiat Oncol Biol Phys, 2007. 69(5): p. 1472-7.
Zapotoczna, A., G. Sasso, J. Simpson, and M. Roach, 3rd, Current role and future perspectives of magnetic resonance spectroscopy in radiation oncology for prostate cancer. Neoplasia, 2007. 9(6): p. 455-63.
 

Publications – 2006

Abdel-Wahab, M., B.A. Berkey, A. Krishan, T. O'Brien, E. Hammond, M. Roach, 3rd, C. Lawton, M. Pilepich, A. Markoe, and A. Pollack, Influence of number of CAG repeats on local control in the RTOG 86-10 protocol. Am J Clin Oncol, 2006. 29(1): p. 14-20.
Aubin, M., O. Morin, J. Chen, A. Gillis, B. Pickett, J.F. Aubry, C. Akazawa, J. Speight, M. Roach, 3rd, and J. Pouliot, The use of megavoltage cone-beam CT to complement CT for target definition in pelvic radiotherapy in the presence of hip replacement. Br J Radiol, 2006. 79(947): p. 918-21.
Chan, L.W. and M. Roach, 3rd, Role of radiation therapy in the treatment of unfavorable risk prostate cancer. Minerva Urol Nefrol, 2006. 58(4): p. 321-7.
Lee, B. and J. Speight, Bladder Cancer, in Handbook of Radiation Oncology, E.K. Hansen and M. Roach, 3rd Editors. 2006, Springer: New York.
Lee, B. and J. Speight, Mesothelioma and Thymoma, in Handbook of Radiation Oncology, E.K. Hansen and M. Roach, 3rd Editors. 2006, Springer: New York.
Lessard, E., S.L. Kwa, B. Pickett, M. Roach, 3rd, and J. Pouliot, Class solution for inversely planned permanent prostate implants to mimic an experienced dosimetrist. Med Phys, 2006. 33(8): p. 2773-82.
Morin, O., A. Gillis, J. Chen, M. Aubin, M.K. Bucci, M. Roach, 3rd, and J. Pouliot, Megavoltage cone-beam CT: system description and clinical applications. Med Dosim, 2006. 31(1): p. 51-61.
Pickett, B., J. Kurhanewicz, J. Pouliot, V. Weinberg, K. Shinohara, F. Coakley, and M. Roach, 3rd, Three-dimensional conformal external beam radiotherapy compared with permanent prostate implantation in low-risk prostate cancer based on endorectal magnetic resonance spectroscopy imaging and prostate-specific antigen level. Int J Radiat Oncol Biol Phys, 2006. 65(1): p. 65-72.
Pouliot, J., O. Morin, M. Aubin, J.F. Aubry, J. Chen, J. Speight, and M. Roach, 3rd, [Megavoltage cone-beam CT: Recent developments and clinical applications]. Cancer Radiother, 2006. 10(5): p. 258-68.
Roach, M., 3rd, In reply to Dr. Cheung. Int J Radiat Oncol Biol Phys, 2006. 66(4): p. 1274-5.
Roach, M., 3rd, M. DeSilvio, R. Valicenti, D. Grignon, S.O. Asbell, C. Lawton, C.R. Thomas, Jr., and W.U. Shipley, Whole-pelvis, "mini-pelvis," or prostate-only external beam radiotherapy after neoadjuvant and concurrent hormonal therapy in patients treated in the Radiation Therapy Oncology Group 9413 trial. Int J Radiat Oncol Biol Phys, 2006. 66(3): p. 647-53.
Roach, M., 3rd, G. Hanks, H. Thames, Jr., P. Schellhammer, W.U. Shipley, G.H. Sokol, and H. Sandler, Defining biochemical failure following radiotherapy with or without hormonal therapy in men with clinically localized prostate cancer: recommendations of the RTOG-ASTRO Phoenix Consensus Conference. Int J Radiat Oncol Biol Phys, 2006. 65(4): p. 965-74.
Roach, M., 3rd, V. Weinberg, M. Nash, H.M. Sandler, P.W. McLaughlin, and M.W. Kattan, Defining high risk prostate cancer with risk groups and nomograms: implications for designing clinical trials. J Urol, 2006. 176(6 Pt 2): p. S16-20.
Shipley, W.U., M. Desilvio, M.V. Pilepich, M. Roach, 3rd, H.B. Wolkov, W.T. Sause, P. Rubin, and C.A. Lawton, Early initiation of salvage hormone therapy influences survival in patients who failed initial radiation for locally advanced prostate cancer: A secondary analysis of RTOG protocol 86-10. Int J Radiat Oncol Biol Phys, 2006. 64(4): p. 1162-7.
Speight, J.L. and M. Roach, 3rd, Radiotherapy in the management of common genitourinary malignancies. Hematol Oncol Clin North Am, 2006. 20(2): p. 321-46.
Speight, J.L. and M. Roach, New techniques and management options for localized prostate cancer. Rev Urol, 2006. 8 Suppl 2: p. S22-9.
Wang-Chesebro, A., P. Xia, J. Coleman, C. Akazawa, and M. Roach, 3rd, Intensity-modulated radiotherapy improves lymph node coverage and dose to critical structures compared with three-dimensional conformal radiation therapy in clinically localized prostate cancer. Int J Radiat Oncol Biol Phys, 2006. 66(3): p. 654-62.
Willoughby, T.R., P.A. Kupelian, J. Pouliot, K. Shinohara, M. Aubin, M. Roach, 3rd, L.L. Skrumeda, J.M. Balter, D.W. Litzenberg, S.W. Hadley, J.T. Wei, and H.M. Sandler, Target localization and real-time tracking using the Calypso 4D localization system in patients with localized prostate cancer. Int J Radiat Oncol Biol Phys, 2006. 65(2): p. 528-34.