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Neurourology and Male Erectile Dysfunction
UCSF is one of the pioneer centers in the world for research
on neurophysiology of voiding dysfunction as well as erectile
dysfunction. The program specializes in diagnosing and treating
complicated voiding problem as well as erectile
dysfunction, priapism
and Peyronie’s
disease. The goal is to continue the quest of improving patient
care through innovative translational research in these two fields.
The UCSF Neurourology Center at Parnassus and Mount Zion is comprised
of a clinical and research component. Clinically an integrated
approach is employed to determine the cause of male sexual dysfunction,
priapism and Peyronie’s disease. Patients are seen at the
UCSF Urology Faculty Practice at the Parnassus campus. The research
component is housed in the Knuppe Molecular Urology Laboratory
at Mt. Zion.
Male Erectile Dysfunction and Peyronie’s Disease
The UCSF Neurourology Center at Mount Zion uses an integrated
approach to determine the cause of male sexual dysfunction. Diagnostic
capabilities include Color Doppler ultrasound, which permits a
noninvasive functional evaluation of the penile arteries, Pyeronie’s
plaque and differentiation of types of priapism. Pharmacologic
cavernosometry and cavernosography are used for the evaluation
of penile veins. The simplest test is the CIS test, a pharmacologic
test of erectile function as a screen test for penile function.
Erectile dysfunction is often treated by one of four methods:
pills (such as Viagra), urethral insert (MUSE), vacuum erection
device, and penile injections. In select cases of blood vessel
blockage or leakage, microvascular surgery may offer a cure. For
those who are not candidate or who fail the above treatment, penile
prosthesis is an excellent alternative.
Peyronie's disease can also be treated with pills, injection,
or surgery depending on the duration and degree of deformity.
Priapism is often a medical emergency and requires color Doppler
or blood gas determination to identify the type of priapism. In
cases of ischemic priapism, injection of medication or a shunting
procedure may be required. For non-ischemic priapism, injection
of a clot or a coil through a catheter placed in the ruptured
penile artery may be needed.
Erectile Dysfunction Research
The urology laboratory at UCSF is one of the premier research
facilities in penile pathophysiology research in the world. Over
the past 20 years, many discoveries related to penile physiology,
pathophysiology, pharmacology, Peyronie’s disease and priapism
have been made here. Current projects include: 1) The use of growth
factors to enhance the formation of new blood vessels in the penis
and thus cure erectile dysfunction due to clogged blood vessel;
2) the mechanism of erectile dysfunction after injury to the cavernous
nerve, a common complication after surgery for cancer of the prostate,
bladder and rectum; 3) innovative approach to re-grow the injured
cavernous nerve; 4) pathophysiology of priapism; 5) new therapies
for Peyronie’s disease.
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Faculty
Tom Lue, MD
Ching-Shwun Lin,
PhD
Guiting Lin,
MD, PhD
Emil Tanagho,
MD
Key Staff
Morgen Ahearn, practice assistant
415/353-7369
Appointments & Locations
UCSF
Medical Center, Parnassus Campus
400 Parnassus Avenue, Suite A-610
San Francisco, CA 94143-0330
Knuppe
Molecular Urology Laboratory
1657 Scott Street, Harold Brunn Institute
Contact Number
To schedule an appointment please call us at 415/353-2200
Patient Handouts
Visit our Patient
Guides to Urological Treatments section to download Patient
Handouts.
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